Carfilzomib Impurity 76 CAS 1809093-03-5 (free base)
| CAS No. | 1809093-03-5 (free base) |
| Molecular Formula | C9H19NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carfilzomib Impurity 76.
As a process- or degradation-related impurity, Carfilzomib Impurity 76 (CAS 1809093-03-5 (free base), C9H19NO3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Carfilzomib Impurity 76 (C9H19NO3C2HF3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 303.28 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carfilzomib Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H19NO3 C2HF3O2 |
| Molecular Weight | 303.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Carfilzomib Standards
- CarfilzomiB impurity 12 (CAS 100564-78-1)
- Carfilzomib Impurity 36 (CAS 1140908-89-9)
- Carfilzomib Impurity 50 (CAS 129603-01-6)
- Carfilzomib Impurity N2 (CAS 1396006-45-3)
- Carfilzomib Impurity N1 (CAS 1396006-47-5)
- Carfilzomib Impurity 28 (CAS 143415-51-4)
- Carfilzomib Impurity 25 (CAS 15136-32-0)
- Carfilzomib Impurity 71 (CAS 1528769-14-3)
Recommended Standards
- Ziprasidone Impurity 13 (CAS CATO-C4X-124013)
- Oxybuprocaine Impurity 9 (CAS CATO-C4X-12279)
- Dexchlorpheniramine EP Impurity B Maleate (CAS 23095-76-3)
- 2-(3-Bromopropyl)tetrahydrofuran (CAS 1004-28-0)
- tert-Butyl 3-isocyanatopropanoate (CAS 884504-55-6)
- N-(2-Isopropyl-6-methylphenyl)pyrazine-2-carboxamide (CAS 545372-95-0)
- 5-Cyclopropoxy-2-methoxybenzamide (CAS 1243450-80-7)
- 2-((3-(Pyridin-4-yl)-1,2,4-oxadiazol-5-yl)methyl)aniline (CAS 1490865-26-3)
- (4-Chloro-2-fluorobenzyl)(phenyl)sulfane (CAS 1443344-76-0)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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